PEBC: What You Need to Know: Sotalol
Indication: atrial fibrillation
Dosing: twice daily, dose reduce in renal impairment
Contraindication: not recommended in heart failure less than 40% ejection fraction due to increased mortality
Adverse Effects:
-torsades de pointes and QT interval prolongation
-bradycardia
-dizziness
-fatigue
Drug Interactions:
-other QT interval prolonging drugs
-careful with other heart rate reducing drugs such as digoxin and calcium channel blockers - reduce sotalol dose by 50%